Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pax6  paired box 6   (Synonyms: 1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Pax-6)
Results	Reference
1	J:230095 Avila A, Vidal PM, Tielens S, Morelli G, Laguesse S, Harvey RJ, Rigo JM, Nguyen L, Glycine receptors control the generation of projection neurons in the developing cerebral cortex. Cell Death Differ. 2014 Nov;21(11):1696-708
1	J:262055 Dhumale P, Menon S, Chiang J, Puschel AW, The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors. PLoS One. 2018;13(4):e0196698
1	J:258293 Divya TS, Lalitha S, Parvathy S, Subashini C, Sanalkumar R, Dhanesh SB, Rasheed VA, Divya MS, Tole S, James J, Regulation of Tlx3 by Pax6 is required for the restricted expression of Chrnalpha3 in Cerebellar Granule Neuron progenitors during development. Sci Rep. 2016 Jul 25;6:30337
1	J:193584 Duan D, Fu Y, Paxinos G, Watson C, Spatiotemporal expression patterns of Pax6 in the brain of embryonic, newborn, and adult mice. Brain Struct Funct. 2013 Mar;218(2):353-72
1	J:99610 Ekonomou A, Kazanis I, Malas S, Wood H, Alifragis P, Denaxa M, Karagogeos D, Constanti A, Lovell-Badge R, Episkopou V, Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1. PLoS Biol. 2005 Jun;3(6):e186
1	J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489
1	J:249823 Guidi LG, Mattley J, Martinez-Garay I, Monaco AP, Linden JF, Velayos-Baeza A, Molnar Z, Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing. Cereb Cortex. 2017 Dec 1;27(12):5831-5845
1	J:104804 Harada C, Harada T, Nakamura K, Sakai Y, Tanaka K, Parada LF, Effect of p75(NTR) on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye. Dev Biol. 2006 Feb 1;290(1):57-65
1	J:279053 Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Fujita K, Musante L, Fischer U, Frints SG, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Muramatsu SI, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H, In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells. Mol Psychiatry. 2015 Apr;20(4):459-71
1	J:74539 Jaskoll T, Zhou YM, Chai Y, Makarenkova HP, Collinson JM, West JD, Hajihosseini MK, Lee J, Melnick M, Embryonic Submandibular Gland Morphogenesis: Stage-Specific Protein Localization of FGFs, BMPs, Pax6 and Pax9 in Normal Mice and Abnormal SMG Phenotypes in FgfR2-IIIc(+/Delta), BMP7(-/-) and Pax6(-/-) Mice. Cells Tissues Organs. 2002;170(2-3):83-98
1*	J:242707 Ji F, Shen T, Zou W, Jiao J, UCP2 Regulates Embryonic Neurogenesis via ROS-Mediated Yap Alternation in the Developing Neocortex. Stem Cells. 2017 Jun;35(6):1479-1492
1	J:175146 Kumbasar A, Plachez C, Gronostajski RM, Richards LJ, Litwack ED, Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei. J Comp Neurol. 2009 Mar 1;513(1):98-112
1	J:123324 Li S, Goldowitz D, Swanson DJ, The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras. Invest Ophthalmol Vis Sci. 2007 Jul;48(7):3292-300
1	J:333826 Loan A, Leung JW, Cook DP, Ko C, Vanderhyden BC, Wang J, Chan HM, Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model. iScience. 2023 Mar 17;26(3):106093
1	J:241324 Martinez-Garay I, Guidi LG, Holloway ZG, Bailey MA, Lyngholm D, Schneider T, Donnison T, Butt SJ, Monaco AP, Molnar Z, Velayos-Baeza A, Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice. Brain Struct Funct. 2017 Apr;222(3):1367-1384
1	J:139387 Marzban H, Kim CT, Doorn D, Chung SH, Hawkes R, A novel transverse expression domain in the mouse cerebellum revealed by a neurofilament-associated antigen. Neuroscience. 2008 Jun 2;153(4):1190-201
1	J:296030 Mestres I, Einsiedel M, Moller J, Cardoso de Toledo B, Smad anchor for receptor activation nuclear localization during development identifies Layers V and VI of the neocortex. J Comp Neurol. 2020 Sep 1;528(13):2161-2173
1	J:208841 Millen KJ, Steshina EY, Iskusnykh IY, Chizhikov VV, Transformation of the cerebellum into more ventral brainstem fates causes cerebellar agenesis in the absence of Ptf1a function. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1777-86
1	J:142509 Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R, Dual requirement for Pax6 in retinal progenitor cells. Development. 2008 Dec;135(24):4037-47
1	J:166211 Qiu Z, Cang Y, Goff SP, Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum. J Neurosci. 2010 Oct 27;30(43):14430-9
1	J:150125 Radakovits R, Barros CS, Belvindrah R, Patton B, Muller U, Regulation of radial glial survival by signals from the meninges. J Neurosci. 2009 Jun 17;29(24):7694-705
1	J:146180 Regad T, Bellodi C, Nicotera P, Salomoni P, The tumor suppressor Pml regulates cell fate in the developing neocortex. Nat Neurosci. 2009 Feb;12(2):132-40
1	J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269
1	J:258738 Shen T, Ji F, Wang Y, Lei X, Zhang D, Jiao J, Brain-specific deletion of histone variant H2A.z results in cortical neurogenesis defects and neurodevelopmental disorder. Nucleic Acids Res. 2018 Mar 16;46(5):2290-2307
1	J:318606 Shen T, Ji F, Yuan Z, Jiao J, CHD2 is Required for Embryonic Neurogenesis in the Developing Cerebral Cortex. Stem Cells. 2015 Jun;33(6):1794-806
1	J:286609 Tait CM, Chinnaiya K, Manning E, Murtaza M, Ashton JP, Furley N, Hill CJ, Alves CH, Wijnholds J, Erdmann KS, Furley A, Rashbass P, Das RM, Storey KG, Placzek M, Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal. PLoS Biol. 2020 Mar;18(3):e3000470
1	J:85590 Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G, Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis. Endocrinology. 2003 Sep;144(9):4061-9
1	J:256150 Voronova A, Yuzwa SA, Wang BS, Zahr S, Syal C, Wang J, Kaplan DR, Miller FD, Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain. Neuron. 2017 May 3;94(3):500-516.e9
1	J:298832 Wang H, Xiao Z, Zheng J, Wu J, Hu XL, Yang X, Shen Q, ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development. Cell Rep. 2019 May 21;27(8):2335-2353.e6
1	J:333924 Wang S, Fu Y, Miyata T, Matsumoto S, Shinoda T, Itoh K, Harada A, Hirotsune S, Jin M, Functional Cooperation of alpha-Synuclein and Tau Is Essential for Proper Corticogenesis. J Neurosci. 2022 Sep 14;42(37):7031-7046
1	J:337816 Wang W, Su L, Ji F, Zhang D, Wang Y, Zhao J, Jiao RD, Zhang M, Huang E, Jiang H, Zhang J, Jiao J, The human FOXM1 homolog promotes basal progenitor cell proliferation and cortical folding in mouse. EMBO Rep. 2022 Feb 3;23(3):e53602
1	J:52402 West-Mays JA, Zhang J, Nottoli T, Hagopian-Donaldson S, Libby D, Strissel KJ, Williams T, AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle. Dev Biol. 1999 Feb 1;206(1):46-62